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Most Profitable Sports - Learn Where the Big Money Is In Sports Betting

One of the most profitable sports to bet on can be European Football (soccer), but in this video I’m only going to take a look at the major North American sports.

Updated 24 Sep 2026 21+ · 1-800-GAMBLER

Last checked

College basketball and college football can also be very profitable to those who follow them closely, with a large number of games played. For this article though we are only going to look at the 4 major professional leagues: NFL, MLB, NBA and NHL.

It is important to note that while statistically some sports might be more profitable for bettors than others, in the end it will all come down to the person who is handicapping the games. Some people will have a great read and great systems in place for one league, and no matter how hard they work they won’t be able to successfully handicap another.

Sportsbooks that take US bets and publish their sign-up terms

These books accept US customers and state the rollover attached to the sign-up offer. Free-bet offers and deposit matches are listed on the same basis so the numbers are comparable line by line.

Ratings last updated: 6 sites checked
  1. 1BetOnline logo

    Online since 2001 · Sportsbook + poker + casino · Crypto · 3–5 min

    Crypto acceptedSportsbookPoker roomFrom $20Panama Gaming Control Board licence
    Sports welcome: 50% free bet up to $250Minimum deposit $20 · Code FREE250
    Bonus detail
    Welcome offerSports welcome: 50% free bet up to $250
    Minimum deposit$20
    Bonus codeFREE250
    WithdrawalsCrypto · 3–5 min
    LicencePanama Gaming Control Board
    Banking

    Deposit routes: Crypto, Card, Wire

    Cryptocurrencies supported: 2

    Typical withdrawal: Crypto · 3–5 min. Card and wire payouts run to several business days at every offshore book, which is why the crypto rail is the one we time.

    Pros and cons
    What works
    • Crypto cashier for same-day withdrawals
    • Sportsbook, poker room and casino share one balance
    • Welcome offer triggers from a $20 deposit
    • Trading since 2001, one of the longest US-facing records
    Watch for
    • No free spins attached to the welcome offer
    • Short coin list — crypto limited to the majors
    • Offer only applies if the code FREE250 is entered on deposit
  2. 2BetUS logo
    BetUS 9.3

    Online since 1994 · Sportsbook + casino · Crypto · 0–1h

    Crypto acceptedSportsbookFrom $100Curacao licence
    Sports welcome: 125% up to $2,500 (100% sportsbook + 25% casino)Wagering 14x sports · Minimum deposit $100 · Code JOIN125
    Bonus detail
    Welcome offerSports welcome: 125% up to $2,500 (100% sportsbook + 25% casino)
    Wagering14x sports
    Minimum deposit$100
    Bonus codeJOIN125
    WithdrawalsCrypto · 0–1h
    LicenceCuracao; Comoros Gambling License Authority
    Banking

    Deposit routes: Crypto, Card, Wire

    Cryptocurrencies supported: 2

    Typical withdrawal: Crypto · 0–1h. Card and wire payouts run to several business days at every offshore book, which is why the crypto rail is the one we time.

    Pros and cons
    What works
    • Crypto cashier for same-day withdrawals
    • One account covers the sportsbook and the casino
    • Trading since 1994, one of the longest US-facing records
    • Headline offer runs to $2,500
    Watch for
    • Needs $100 in to claim the welcome offer
    • No free spins attached to the welcome offer
    • Short coin list — crypto limited to the majors
  3. 3Bovada logo
    Bovada 9.0

    Online since 2011 · Sportsbook + poker + casino · Crypto · 10–15 min

    Crypto acceptedSportsbookPoker roomFrom $10Curacao licence
    Crypto sports welcome: 75% up to $750 with a 5x rolloverWagering 5x · Minimum deposit $10 · Code BTCSWB750
    Bonus detail
    Welcome offerCrypto sports welcome: 75% up to $750 with a 5x rollover
    Wagering5x
    Minimum deposit$10
    Bonus codeBTCSWB750
    WithdrawalsCrypto · 10–15 min
    LicenceCuracao
    Banking

    Deposit routes: Crypto, Card, Wire

    Cryptocurrencies supported: 2

    Typical withdrawal: Crypto · 10–15 min. Card and wire payouts run to several business days at every offshore book, which is why the crypto rail is the one we time.

    Pros and cons
    What works
    • Crypto cashier for same-day withdrawals
    • Sportsbook, poker room and casino share one balance
    • Welcome offer triggers from a $10 deposit
    Watch for
    • No free spins attached to the welcome offer
    • Short coin list — crypto limited to the majors
    • Offer only applies if the code BTCSWB750 is entered on deposit
  4. 4Xbet logo
    Xbet 8.6

    Online since 2013 · Sportsbook + casino · Crypto · instant

    Crypto acceptedSportsbookFrom $45
    Sports welcome: 100% up to $200 (crypto) / 50% up to $200 (card)Wagering 10x · Minimum deposit $45 · Code XBCRYPTO100
    Bonus detail
    Welcome offerSports welcome: 100% up to $200 (crypto) / 50% up to $200 (card)
    Wagering10x
    Minimum deposit$45
    Bonus codeXBCRYPTO100
    WithdrawalsCrypto · instant
    Banking

    Deposit routes: Crypto, Card, Wire

    Cryptocurrencies supported: 1

    Typical withdrawal: Crypto · instant. Card and wire payouts run to several business days at every offshore book, which is why the crypto rail is the one we time.

    Pros and cons
    What works
    • Crypto cashier for same-day withdrawals
    • One account covers the sportsbook and the casino
    Watch for
    • Needs $45 in to claim the welcome offer
    • No free spins attached to the welcome offer
    • Short coin list — crypto limited to the majors
  5. 5MyBookie logo

    Online since 2014 · Sportsbook + casino · Crypto · 0–1h

    3 cryptocurrenciesSportsbookFrom $50
    Sports welcome: 100% up to $1,000Wagering 10x · Minimum deposit $50 · Code MYB100
    Bonus detail
    Welcome offerSports welcome: 100% up to $1,000
    Wagering10x
    Minimum deposit$50
    Bonus codeMYB100
    WithdrawalsCrypto · 0–1h
    Banking

    Deposit routes: Crypto, Card, Wire

    Cryptocurrencies supported: 3

    Typical withdrawal: Crypto · 0–1h. Card and wire payouts run to several business days at every offshore book, which is why the crypto rail is the one we time.

    Pros and cons
    What works
    • Crypto cashier for same-day withdrawals
    • One account covers the sportsbook and the casino
    Watch for
    • Needs $50 in to claim the welcome offer
    • No free spins attached to the welcome offer
    • Offer only applies if the code MYB100 is entered on deposit
  6. 6SportsBetting.ag logo

    Online since 2003 · Sportsbook + poker + casino · Crypto · 10–15 min

    4 cryptocurrenciesSportsbookPoker roomFrom $50Panama Gaming Control Board licence
    Sports welcome: 50% up to $250 in free bets plus 100 free spinsMinimum deposit $50 · No code needed
    Bonus detail
    Welcome offerSports welcome: 50% up to $250 in free bets plus 100 free spins
    Minimum deposit$50
    Bonus codeNone required
    WithdrawalsCrypto · 10–15 min
    LicencePanama Gaming Control Board
    Banking

    Deposit routes: Crypto, Card, Wire

    Cryptocurrencies supported: 4

    Typical withdrawal: Crypto · 10–15 min. Card and wire payouts run to several business days at every offshore book, which is why the crypto rail is the one we time.

    Pros and cons
    What works
    • Banks in 4 cryptocurrencies, so withdrawals clear in minutes
    • Sportsbook, poker room and casino share one balance
    • Trading since 2003, one of the longest US-facing records
    Watch for
    • Needs $50 in to claim the welcome offer
    • No free spins attached to the welcome offer

Advertising disclosure. Links marked “Visit” are commercial and we may be paid when you open an account through them. That does not change the order above: it follows the offer terms, the banking and the operating record. 21+ only. Gambling should be entertainment, never income — if it stops being that, call 1-800-GAMBLER.

It’s a Numbers game…

Let’s take a look at how many regular season betting opportunities we get for each major league:

  • NFL = 256 games per season
  • NHL = 1230 games per season
  • NBA = 1230 games per season

And with a 162 game schedule the MLB offers 2430 games per season to bet on.

Also factor in that easily the most popular sport for betting is the National Football League and you can conclude that the sharpest of bettors analyze those 256 games to shreds.

OK, so MLB has the advantage in total games available to bet on, now lets take a look at the odds offered on each sport.

Odds Offered

While most sportsbooks offer 10-20 cent lines on NFL, NBA and NHL games they get extremely competitive with their MLB lines offering as low as 5-8 cent moneylines.

This means that while in an evenly matched NFL game you might see the Steelers -110 and the Ravens -110, in an evenly matched MLB game you can expect to see something like Cardinals -104 and the Reds -104.

Again, point MLB.

I’ve got the last final blow that makes MLB baseball the most profitable sport to bet on.

Betting Match Ups

The NHL, NBA, and NFL have something in common that, if looked at in a unique way, the MLB does not. The first three are team sports. All 11,6, or 5 players are on the field, ice or court at the same time and they must play as a team to win their game. If a few players aren’t playing well it can bring the whole team down.

I know you might be saying “well the MLB is the same way”. It is in some aspects as a few players playing poorly can cost the team the game, but overall from a betting perspective you can look at MLB as one on one match ups. It is essentially pitcher vs batter match ups. Defensive, managing, base running, and that does play a role, but most games are won and lost in the pitcher vs hitter match up.

There are so many stats to analyze in baseball as well that makes it that much better for us sports bettors.

To Recap

  • MLB betting offers the most opportunities with 2430 games in the regular season.
  • We can get better lines on MLB games.
  • MLB is more of a one on one match up with lots of stats compared to the others which are more team games.

With that said some people simply can’t find profitable angles in the MLB. Those bettors might be great at NFL or NBA betting. Find what you are most profitable betting and continue working on your strengths.